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Essay on dementia Composition of Chinese red-yeast-rice dietary supplement More recently, red yeast rice extract, taken in a supplemental form, has been found to lower cholesterol.
More specifically, the extract is a source of a number of compounds known as statins - the compounds largely held responsible for reducing cholesterol levels.
It appears to accomplish this by blocking a key enzyme in the liver. As such, red yeast rice gained recognition in the United States as a cholesterol-lowering agent. Red yeast rice extract was introduced to the U.
In fact, red yeast rice is almost identical to lovastatin, which is the key ingredient in the statin drug Mevacor. Procedures followed were in accord with the ethical standards set forth in the Helsinki Declaration of as revised in As required by the Human Subject Protection Review Committee, all subjects were told about possible rare side effects of liver and muscle toxicity observed with cholesterol-lowering drugs.
All subjects provided written, informed consent to participate. Patients were randomly assigned to the Chinese red-yeast-rice dietary supplement— Cholestin, Pharmanex, Inc, Simi Valley, CA and placebo-treated groups.
Does anyone know Rice supplement prompt Studies in humans have been conducted in China with both more and less concentrated extracts of the red yeast rice than in our red-yeast-rice—treated group. In hypercholesterolemic subjects treated with Xuezhikang 1.
Two to 4 wk before the initiation of this study, subjects were instructed to cease taking all medications and were provided with dietary counseling.
In a second study, an earlier version of the red-yeast-rice supplement containing 10—13 mg total monacolins was given to hypercholesterolemic subjects. Total cholesterol decreased by HDL-cholesterol concentrations increased by These and other Chinese studies were similar to this study in showing a marked effect of the constituents of this dietary supplement on cholesterol concentrations.
However, there were differences in the ethnicity and serum lipid concentrations of the populations studied. Furthermore, a rice placebo was used in the present study in a double-blind fashion, whereas the Chinese studies used different natural preparations in the comparison group rather than a matched placebo capsule.
Rice Supplement - Improve your health Concerned about the high levels of lovastatin in some products, the FDA in August banned the sale of Cholestrix, a red yeast rice supplement sold by Sunburst Biorganics, and two other red yeast rice supplements sold by Swanson Health Products. The FDA reports that the levels of lovastatin found in the products could be high enough to cause kidney damage, a rare complication of statins.
Red Yeast Rice Supplement Walgreens Rice Supplement Essay - College Confidential This study was an important first step in establishing that the observed effects of red yeast rice in China were not due to diet alone but could be clearly related to this Chinese red-yeast-rice dietary supplement in a placebo-controlled, randomized trial.
This study also established the need for a study on the long-term safety and efficacy of this supplement in a larger population. The effects observed on triacylglycerol concentrations and HDL-cholesterol concentrations in the Chinese studies also need to be examined in future studies by using carefully controlled diets in appropriately selected populations.
You can buy them alone or combined with other ingredients such as CoQ But when it comes to purchasing red yeast rice supplements, the saying 'buyer beware' rings true. Because it's illegal for red yeast rice supplements to contain more than trace amounts of lovastatin in the U.
As a result, while a product may specify it contains a certain amount of red yeast rice, there's no way to know the actual monacolin content or how the ingredients were processed. We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice supplement in an American population consuming a diet similar to the American Heart Association Step I diet using a double-blind, placebo-controlled, prospectively randomized wk controlled trial at a university research center.
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